Medieval knights dedicated to healthcare.

Hospitaller Malta, known in Maltese history as the Knights' Period, was a de facto state which existed between 1530 and 1798 when the Mediterranean islands of Malta and Gozo were ruled by the Order of St. John of Jerusalem.

Saint Julian the Hospitaller is a saint venerated in the Roman Catholic Church and Eastern Orthodox Church.

The history of Rhodes under the Order of Saint John lasted from 1310 until 1522.

The Hospitaller colonization of the Americas occurred during a 14-year period in the 17th century in which the Knights Hospitaller of Malta, at the time a vassal state of the Kingdom of Sicily, led by the Italian Grand Master Giovanni Paolo Lascaris, possessed four Caribbean islands: Saint Christopher, Saint Martin, Saint Barthélemy, and Saint Croix.

The Hospitaller conquest of Rhodes took place in 1306–1310.