Usually means: Simulation or analysis done computationally.
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We found 9 dictionaries that define the word in silico:

General (5 matching dictionaries)
  1. in silico: Merriam-Webster
  2. in silico: The Word Spy
  3. in silico: Wiktionary
  4. In Silico (Pendulum album), In Silico, In silico (disambiguation), In silico: Wikipedia, the Free Encyclopedia
  5. In silico: World Wide Words

Business (1 matching dictionary)
  1. BuzzWhack (No longer online)

Computing (1 matching dictionary)
  1. in silico: Netlingo

Medicine (2 matching dictionaries)
  1. in silico: Merriam-Webster Medical Dictionary
  2. Hypermedia Glossary Of Genetic Terms (No longer online)

Definitions from Wikipedia (In silico)

noun:  In biology and other experimental sciences, an in silico experiment is one performed on a computer or via computer simulation software.
noun:  an expression meaning "performed on computer or via computer simulation".

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