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We found one dictionary that defines the word self-iso:

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  1. self-iso: Wiktionary

Definitions from Wiktionary (Self-iso)

noun:  (informal) Short for self-isolation. [(chiefly epidemiology) Voluntary isolation from others, especially in order to avoid spreading a communicable disease.]
verb:  (informal) Short for self-isolate. [(epidemiology) To quarantine or isolate oneself from others, especially in order to avoid spreading a communicable disease.]

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