Usually means: Skin irritation from prolonged riding.
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We found 21 dictionaries that define the word saddle sore:

General (18 matching dictionaries)
  1. saddle sore: Longman Dictionary of Contemporary English
  2. saddle sore: Merriam-Webster
  3. saddle sore: American Heritage Dictionary of the English Language
  4. saddle-sore, saddle-sore: Collins English Dictionary
  5. saddle-sore, saddle sore: Vocabulary.com
  6. saddle-sore: Wordnik
  7. saddle-sore: Cambridge Advanced Learner's Dictionary
  8. saddle sore: Wiktionary
  9. saddle sore: The Wordsmyth English Dictionary-Thesaurus
  10. saddle sore: Infoplease Dictionary
  11. saddle-sore, saddle sore: Dictionary.com
  12. Saddle sore: Wikipedia, the Free Encyclopedia
  13. saddle-sore, saddle sore: Rhymezone
  14. saddle-sore, saddle sore: FreeDictionary.org
  15. saddle-sore, saddle sore: Mnemonic Dictionary
  16. saddle-sore, saddle sore: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. saddle sore: Encyclopedia

Medicine (2 matching dictionaries)
  1. Saddle sore: MedTerms.com Medical Dictionary
  2. Saddle sore: Drug Medical Dictionary

(Note: See saddle_sores as well.)

Definitions from Wiktionary (saddle sore)

noun:  A gall, a sore developed by a horse from an ill-fitting or ill-adjusted saddle.
noun:  A sore developed by a horseback rider or a cyclist caused by a saddle.
adjective:  Pertaining to a horse with saddle sores, or to a rider who has been riding too long.

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