Usually means: Immunity developed before exposure occurs.
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We found 7 dictionaries that define the word premune:

General (5 matching dictionaries)
  1. premune: Merriam-Webster
  2. premune: Collins English Dictionary
  3. premune: Dictionary.com
  4. premune: TheFreeDictionary.com
  5. premune: Wiktionary

Medicine (2 matching dictionaries)
  1. premune: Merriam-Webster Medical Dictionary
  2. premune: Medical dictionary

Definitions from Wiktionary (premune)

adjective:  (medicine) Immune to a disease through having had it before.

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