Usually means: Experience failure or misfortune significantly.
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We found 12 dictionaries that define the word come to grief:

General (11 matching dictionaries)
  1. come to grief: Merriam-Webster
  2. come to grief: Oxford Learner's Dictionaries
  3. come to grief: Collins English Dictionary
  4. come to grief: Cambridge Advanced Learner's Dictionary
  5. come to grief: Wiktionary
  6. come to grief: Dictionary.com
  7. Come to Grief: Dictionary of Phrase and Fable (1898)
  8. come to grief: TheFreeDictionary.com
  9. come to grief: Longman Dictionary of Contemporary English

Miscellaneous (1 matching dictionary)
  1. come to grief: Idioms

Definitions from Wiktionary (come to grief)

verb:  (idiomatic) To suffer a disastrous outcome.

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