Sorry, no online dictionaries contain the exact phrase opposite of designate.
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Reverse dictionary results:
1. counter
 2. express
3. homonym
4. pole
5. poles
6. prick
7. shake
8. shakes
9. shaking
10. odd
 11. cipher
12. madam
13. saint
14. appoint
15. assign
16. assigned
17. assigning
18. blaze
19. blazed
20. call
 21. constituent
22. constitute
23. constituted
24. declare
25. denominate
26. denote
27. designated
28. destined
29. doom
30. doomed
 31. elect
32. elected
33. expressing
34. fee
35. foom
36. initialize
37. label
38. mark
39. mean
40. name

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You can look up the words in the phrase individually using these links:   opposite ?   of ?   designate ?
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oppo*to search for words beginning with oppo, or
*nateto search for words ending with nate
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